Survival after transcatheter aortic valve replacement appears to be high

Analysis of data from real clinical practice showed that the eight-year survival rate for transcatheter aortic valve implantation in patients with severe aortic stenosis reaches 95% in people under 75 years of age from the lowest risk group. The overall five-year survival rate is 92.9%. Survival rates were higher in people with higher left ventricular ejection fraction.

Scientists from the University of Michigan and the University of Virginia assessed long-term survival after transcatheter aortic valve replacement for severe aortic stenosis in low-risk patients. The study results were published in the journal The Annals of Thoracic Surgery.

The five-year survival rate after transcatheter aortic valve implantation was 92.9%. The eight-year survival rate approached 90%, reaching 95% in the lowest-risk patients under 75 years of age. Survival also depended on left ventricular ejection fraction and was higher in people with higher values.

Data from 42,586 patients who underwent isolated transcatheter aortic valve replacement at cardiac surgery centers in the United States were analyzed. The average age of the participants was 74.2 years. At baseline, all selected patients had a low risk of postoperative mortality. Overall mortality rates were assessed over different periods of time.

The authors noted that transcatheter aortic valve replacement is considered an excellent primary option for higher-risk or older patients, with the surgical method showing high survival rates for low-risk older adults. Today, this finding provides physicians and patients with a choice of the primary method of aortic valve replacement in cases of severe stenosis depending on the predicted risk of mortality.

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