Percutaneous coronary intervention reduced mortality in elderly patients


Japanese scientists studied the effect of percutaneous intervention on in-hospital outcomes in patients with myocardial infarction. The results showed the advantage of the method even in people over 80 years of age.

Scientists from the University of Tokyo, Iwate Medical University and Yamagata University School of Medicine assessed the effect of percutaneous coronary intervention on in-hospital all-cause mortality and the incidence of in-hospital cardiac death in patients with ST-segment elevation myocardial infarction complicated by cardiogenic shock (STEMICS). The study results were published in the European Heart Journal Acute Cardiovascular Care.




The study included 2760 patients with ST-segment elevation myocardial infarction complicated by cardiogenic shock. There were 789 (28.6%) participants aged 80 years or older. 89.2% of patients under 80 years of age and 80.9% of the older group underwent percutaneous intervention. The success rate of percutaneous intervention was 85.3%.

In-hospital outcomes varied significantly by percutaneous intervention status and age. In the group younger than 80 years, in-hospital all-cause mortality among those treated with intervention was 27.9% compared with 47.9% among patients without intervention. Among participants aged 80 years and older, in-hospital mortality was 40.6% after percutaneous intervention compared with 67.5% without it.

The rate of in-hospital cardiac death in the group under 80 years of age was 20.9% versus 35.7%. In the older group, the figure reached 33.1 and 60.3%, respectively. After adjusting for confounders, in patients older than 80 years, percutaneous intervention was independently associated with a lower incidence of in-hospital cardiac death but was not associated with in-hospital all-cause mortality.

Mortality rates in the oldest group were significantly higher than among patients under 80 years of age: in-hospital all-cause mortality was 45.8% versus 30.1%. The rate of in-hospital cardiac death is 38.3% compared to 22.5%.

The results obtained in Japan may help in choosing management tactics for elderly patients with STEMICS in other countries.



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