The researchers found that patients who took statins before developing intracerebral hemorrhage were less likely to have a subsequent stroke, and ischemic stroke in particular. However, the likelihood of recurrent intracerebral hemorrhage did not increase.
Scientists from the University of Southern Denmark, the University of Kentucky and Harvard Medical School assessed the effect of statins on the risk of stroke among survivors of intracerebral hemorrhage. The study results were published in the journal Neurology.
An analysis that adjusted for factors including hypertension, diabetes and alcohol intake found that statins reduced the overall risk of stroke by 12% and the risk of ischemic stroke by 21%. However, treatment with statins did not increase the risk of recurrent hemorrhage.
|We analyzed data from more than 15 thousand patients at least 50 years of age who were hospitalized in Danish hospitals due to newly diagnosed intracerebral hemorrhage. The average age of the participants was 73 years, and all of them survived more than 30 days from hospitalization. The effect of taking statins before hospitalization on the likelihood of developing a subsequent stroke was assessed.
During 3.3 years of follow-up, 1959 cases of stroke were identified. Ischemic stroke was diagnosed in 1073 participants, repeated intracerebral hemorrhage – in 984. The control group consisted of 7400 people of similar sex and age without the disease. Among the participants who developed a stroke, 757 were taking statins. In the control group, 3044 patients used the drugs.
The authors noted that additional randomized studies are needed to confirm these results.