American researchers have developed a blood test for Parkinson’s disease

Experts from the American Duke University have developed a blood test that can detect Parkinson’s disease.

Researchers at Duke University in North Carolina have developed a blood test that can detect Parkinson’s disease. The results of the patient study were published in the journal Science Translational Medicine.

Now the disease is diagnosed based on clinical symptoms after the patient has suffered neurological damage. According to Associate Professor of Neurology and Pathology at Duke University School of Medicine Laurie Sandersa new blood test will make it possible to diagnose the disease earlier and begin treatment.

The test measures DNA damage in mitochondria. A number of studies have shown that mitochondrial DNA damage is associated with Parkinson’s disease. The team used polymerase chain reaction (PCR) technology to create the test, and it was able to successfully detect higher levels of mitochondrial DNA damage in the blood cells of patients with Parkinson’s disease compared to people without the disease.

The test also found high levels of damaged DNA in blood samples from people with the LRRK2 genetic mutation, which is associated with an increased risk of the disease. The test identifies Parkinson’s disease patients with and without LRRK2 mutations.

Sanders said she hopes the test will also help develop drugs that can reverse or stop mitochondrial DNA damage and the disease process, as well as identify patients who might benefit from these drugs.

Source link