Polycystic ovary syndrome increased the risk of cardiovascular complications during childbirth

Polycystic ovarian disease has contributed to an increased risk of preeclampsia, eclampsia, cardiomyopathy and heart failure in pregnant women. It also increased the cost and duration of hospitalization.

Women with polycystic ovary syndrome showed a higher risk of developing cardiovascular complications during childbirth. Hospitalization among patients with this diagnosis is associated with increased duration and cost of treatment. The results of the study are presented in Journal of the American Heart Association.

Data from the 2002–2019 National Inpatient Sample were used. International Classification of Diseases, Ninth and Tenth Revision codes were used to identify hospitalizations for labor and diagnosis of polycystic ovary disease.

A total of 71 million hospitalizations for childbirth were identified, of which 0.3% were among women with polycystic ovary syndrome (195,675). The average age of patients with ovarian pathology was 31 years. Among concomitant pathologies, diabetes and dyslipidemia were more common. After adjusting for age, race/ethnicity, comorbidities, insurance, and income, polycystic disease remained an independent predictor of cardiovascular complications, including preeclampsia, eclampsia, peripartum cardiomyopathy, and heart failure, compared with no polycystic ovarian disease.

In women with ovarian pathology, hospitalization during childbirth is associated with increased duration (three days versus two days) and cost ($4,901 versus $3,616).

The study highlights the importance of optimizing the cardiovascular health of women with polycystic ovary syndrome before, during and after pregnancy to prevent the development of cardiovascular complications.

Polycystic ovary syndrome is an endocrine disorder characterized by irregular menstrual cycles (ovulatory dysfunction), hyperandrogenism, and polycystic ovaries on imaging. Mainly observed in women of reproductive age. Its prevalence ranges from 3 to 10%.

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