Mortality from hepatitis B in Russia has increased over the past 30 years » Medvestnik

The global prevalence of HBV infection has shown a decreasing trend, especially among children under five years of age. There has been a decrease in hepatitis-related mortality rates in the world, but not in Russia.

According to a study published in The Lancet Gastroenterology and Hepatology, from 1990 to 2019 there was a decrease in the incidence of hepatitis B, mainly in the younger age group (children under 5 years of age). Vaccination contributed to the improvement of the epidemic situation. There was also a decrease in mortality rates.

The global prevalence of chronic HBV infection among all ages was 4.1%, which corresponds to 316 million infected people. Data provided for 2019.

Between 1990 and 2019, the prevalence of infection among all ages fell by 31.3%, with a more marked decline among children under five years of age, at 76.8%.

In Russia, the mortality rate from hepatitis B during the study period increased from 2.8 to 4.8 per 100 thousand people among all ages. However, the detection rate of infection has decreased from 0.9% in 1990 to 0.6% in 2019. A pronounced decrease in the indicator occurred due to children under five years of age: from 0.7 to 0.03%.

As of 2019, 68 of 194 countries had already achieved the 2030 WHO Interim Guidance target of four hepatitis B deaths per 100,000 people across all age groups.

To achieve the 2030 targets, the world needs to accelerate efforts to combat hepatitis B. These include vaccination, testing and treatment. These interventions must be strategically supported and expanded to achieve disease elimination.

Data from serological studies of the population, extracts, and registers were assessed. Scientists studied rates of chronic HBV infection and associated complications – cirrhosis and liver cancer.

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